Articles

P3.11 Remitting seronegative symmetrical synovitis with pitting edema after allogeneic stem cell transplantation

BJH - volume 6, issue Abstract Book BHS, january 2015

A. Devresse , S. Daens , R. Lhommel , L. Knoops MD, PhD, D. Bauwens , E. Van den Neste MD, PhD, X. Poiré MD, PhD

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P3.15 Clofarabine as salvage therapy and bridge to transplantation in acute leukemia. A single center experience

BJH - volume 6, issue Abstract Book BHS, january 2015

G. Di Prinzio , C. Cornil , E. Collinge MD, A. Devresse , P.D.M. Katoto , V. Havelange MD, PhD, E. Van den Neste MD, PhD, X. Poiré MD, PhD, M-C. Vekemans MD

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P1.15 Outcome after salvage chemotherapy with DHAP/ICE-type regimens and attempt to transplant in patients with aggressive lymphoma: experience of a single centre

BJH - volume 6, issue Abstract Book BHS, january 2015

P.D.M. Katoto , N. Vanlangendonck , V. Havelange MD, PhD, X. Poiré MD, PhD, C. Lambert MD, M-C. Vekemans MD, A. Ferrant , V. Lannoy , E. Van den Neste MD, PhD

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Treatment of mantle cell lymphomas: recommendations of the Belgian Hematological Society

BJH - volume 5, issue 3, september 2014

E. Mourin MD, A. Van Hoof MD, PhD, A. Bosly MD, PhD, C. Bonnet MD, PhD, V. De Wilde MD, PhD, C. Doyen MD, PhD, C. Hermans MD, PhD, A. Janssens MD, PhD, L. Michaux MD, PhD, W. Schroyens MD, PhD, A. Sonet MD, E. Van den Neste MD, PhD, G. Verhoef MD, PhD, P. Zachée MD, PhD, M. André MD, PhD

Summary

Mantle cell lymphoma was recognised in the nineties and is characterised by the t(11;14)(q13;q32) translocation which results in overexpression of cyclin D1.1 This disease represents approximately 6% of all non-Hodgkin’s lymphomas. Mantle cell lymphoma generally affects patients over 60 years-old. Most patients have advanced disease (>70 % Ann Arbor stage IV). Several efforts have been made to predict outcome in mantle cell lymphoma. The cell-proliferation marker Ki-67, the Mantle Cell Lymphoma International Prognostic Index, fluorodeoxyglucose positron emission tomography and minimal residual disease are prognostic tools. For young patients, chemoimmunotherapy followed by high-dose chemotherapy plus stem cell transplantation is the treatment of choice. For the main group of older patients, chemo-immunotherapy followed by maintenance with rituximab is the gold standard. In relapses, temsirolimus is actually registered and new drugs, such as ibrutinib, are currently evaluated with promising preliminary results.2–5

(BELG J HEMATOL 2014;5(3):89–96)

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Syndrome of inappropriate antidiuretic hormone secretion associated with bortezomib

BJH - volume 5, issue 3, september 2014

P. Mineur MD, F. Hubert , E. Van den Neste MD, PhD, K. Peeters PhD

Summary

We observed severe hyponatremia in a patient who was treated with bortezomib for multiple myeloma. The patient was diagnosed with the syndrome of inappropriate secretion of antidiuretic hormone due to bortezomib.

(BELG J HEMATOL 2014;5(3):104–5)

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BHS guidelines for the treatment of marginal zone lymphomas

BJH - volume 5, issue 1, march 2014

D. Bron MD, PhD, E. Van den Neste MD, PhD, A. Kentos MD, PhD, F. Offner MD, PhD, W. Schroyens MD, PhD, C. Bonnet MD, PhD, A. Van Hoof MD, PhD, G. Verhoef MD, PhD, A. Janssens MD, PhD

Summary

Marginal zone lymphomas are a heterogeneous subtype of indolent B-non-Hodgkin Lymphoma that includes three distinct diseases: Extranodal mucosa associated lymphoid tissue lymphoma, nodal marginal zone lymphoma and splenic marginal zone lymphoma lymphocytes +/− villous lymphocytes. The different diagnosis, work up and treatment options are discussed in these guidelines.

(BELG J HEMATOL 2014;5(1):12–21)

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P4.16 Pneumomediastinum as a complication of allogeneic bone marrow transplantation

BJH - volume 5, issue Abstract Book BHS, january 2014

J. Devreux , G. David , A. Dermine , V. Havelange MD, PhD, B. Ghaye , E. Van den Neste MD, PhD, L. Michaux MD, PhD, X. Poiré MD, PhD, M-C. Vekemans MD

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