Volume 6, Abstract Book BSTH, November 2015

Index

ABSTRACTS

Dextran sulphate triggers platelet aggregation via direct activation of PEAR1

C. Vandenbriele, Y. Sun, M. Criel, K. Cludts, S. van Kerckhoven, B. Izzi, T. Vanassche, P. Verhamme, M.F. Hoylaerts


The order of draw: much ado about nothing?

C. Indevuyst, W. Schuermans, E. Bailleul, P. Meeus


Comparison of HIL interferences on three hemostasis analyzers and contribution of a preanalytical module for routine coagulation assays

C. Nagant, L. Rozen, A. Demulder


Phenotypic characterization of a patient with Glanzmann Thrombasthenia caused by a novel homozygous mutation in the ITGA2B gene

C. Lecut, P. Péters, M. Fiore, C. Delierneux, M. Joiret, A. Hego, C. Oury, A. Gothot


Pneumatic tube transport is feasible for Rotem coagulation tests in a Central laboratory

L. Moreno Y Banuls, R. Li, C. Swaelens, S. Bargaga, B. Kreps, P. Mols, P. Goffard, A. Roman, P. Kapessidou, B. Cantinieaux


Clotting time or Rosner index for mixing test interpretation makes a difference in the overall lupus anticoagulant test result

B. Depreter, K. Devreese


An epidemiological evaluation of the incidence of deep venous thrombosis and pulmonary embolism in patients with hip or knee replacement surgery and of its impact on the average length of stay and hospitalization cost

P. Chevalier, M. Lamotte


Comparison of point-of-care instruments I-STAT, ACTPlus and Hemochron Signature Plus for measurement of activated clotting time (ACT)

S. Vandendriessche, H. Laverge, K. Devreese


Endogenous plasmin levels control the development of acute episodes of thrombotic thrombocytopenic purpura in mice

C. Tersteeg, L. Deforche, F. Denorme, A. Gils, R. Lijnen, H. Deckmyn, P.J. Declerck, H. Rottensteiner, S.F. De Meyer, C. Maas, K. VanHoorelbeke


Assessment of sensitivity for coagulation factor deficiency in routine coagulation tests

E. Dumoulin, L. Fiers, K. Devreese


ADAMTS13-induced destabilization of the von Willebrand factor A2 domain

L. Deforche, H.B. Feys, K. De Ceunynck, A. Vandenbulcke, N. VanDePutte, E. Roose, Y. Fujimura, K. Soejima, D.A. Lane, B.M. Luken, H. Deckmyn, J.E. Sadler, S.F. De Meyer, K. VanHoorelbeke


A mouse model for acquired thrombotic thrombocytopenic purpura

L. Deforche, C. Tersteeg, E. Roose, A. Vandenbulcke, N. VanDePutte, E. De Cock, H. Rottensteiner, H. Deckmyn, S.F. De Meyer, K. VanHoorelbeke


Phosphorylation of platelet acetyl-CoA carboxylase is increased in human and mice atherosclerosis and could be an indicator of persistent thrombin generation

S. Lepropre, S. Kautbally, M.-B. Onselaer, D. Vancraeynest, N. Barrile, L. Bertrand, J.-L. Vanoverschelde, C. Beauloye, S. Horman


Identification of a novel staphylococcal binding partner for soluble von Willebrand factor-binding protein crucial for adhesion of Staphylococcus aureus to the vessel wall via von Willebrand factor

J. Claes, M. Peetermans, L. Liesenborghs, T.R. Veloso, M.F. Hoylaerts, R. Heying, P. Verhamme, T. Vanassche


ADAMTS13 deficiency in mice does not aggravate diet-induced liver steatosis

L. Geys, E. Roose, K. VanHoorelbeke, M. Hoylaerts, L. Roger, I. Scroyen


GARP expressed on platelets does not contribute to hemostasis and thrombosis in mice

E. Vermeersch, S. De Meyer, K. VanHoorelbeke, D. Unutmaz, H. Fujii, H. Deckmyn, C. Tersteeg


Binding to von Willebrand factor enables S. lugdunensis to overcome shear stress and cause infective endocarditis

L. Liesenborghs, M. Peetermans, J. Claes, M. Lox, K. Cludts, S. van Kerckhoven, W. Peetermans, T. Vanassche, M. Hoylaerts, P. Verhamme


P2X1 ion channels limit the formation of extra-intestinal neutrophil-rich thrombi in acute colitis

O. Wéra, C. Delierneux, A. Hego, C. Lecut, L. Servais, P. Lancellotti, C. Oury


ADAMTS13 containing the naturally occurring mutation p.Arg1177Gln adopts an open conformation

E. Roose, R. Demeersseman, I. Pareyn, D. Dierickx, L. Deforche, H. Deckmyn, S. De Meyer, K. VanHoorelbeke


Addition of idarucizumab to plasma samples containing dabigatran allows to use routine coagulation assays to diagnose hemostasis disorders

M. Peetermans, J. Toelen, J. Schoeters, K. Peerlinck, J. Van Ryn, T. Vanassche, P. Verhamme, M. Jacquemin


A novel FGA mutation underlying a case of congenital dysfibrinogenemia with unusual clinical presentation

M. Tajdar, M. Herpol, C. Orlando, B. De Bisschop, P. Govaert, K. Jochmans


Elevated basal levels of platelet-bound fibrinogen predict the occurrence of sepsis in ICU: a prospective study

C. Delierneux, N. Layios, A. Hego, J. Huart, A. Joly, P. Geurts, P. Damas, C. Lecut, A. Gothot, C. Oury


The role of ADAMTS13 and VWF in Patients with Acute Ischemic Stroke: a Case Control Study

F. Denorme, P. Kraft, C. Drechsler, I. Pareyn, G. Stoll, K. VanHoorelbeke, H. Deckmyn, P.U. Heuschmann, C. Kleinschnitz, S.F. De Meyer


High and long-term expression of von Willebrand factor after Sleeping Beauty transposon-mediated gene therapy in mice

I. Portier, K. VanHoorelbeke, S. Verhenne, I. Pareyn


Platelet Endothelial Aggregation Receptor 1: a novel modifier of neo-angiogenesis

C. Vandenbriele, A. Kauskot, I. Vandersmissen, M. Criel, R. Geenens, S. Craps, A. Luttun, S. Janssens, M.F. Hoylaerts, P. Verhamme


ADAMTS13-mediated thrombolysis of t-PA resistant occlusions in ischemic stroke

F. Denorme, F. Langhauser, L. Desender, A. Vandenbulcke, H. Rottensteiner, B. Plaimauer, T. Andersson, O. François, H. Deckmyn, F. Scheiflinger, C. Kleinschnitz, K. VanHoorelbeke, S.F. De Meyer


Endothelial cells do not express the vasopressin receptor 2 that is required for the release of FVIII and VWF following DDAVP treatment

L. Feyen, B. Izzi, R. Lavend’homme, T. Shahani, K. Peerlinck, M. Jacquemin


Inhibition of TAFI and PAI-1 protects mice from cerebral ischemia/reperfusion injury

F. Denorme, T. Wyseure, N. VanDePutte, M. Peeters, H. Deckmyn, A. Gils, K. VanHoorelbeke, P.J. Declerck, S.F. De Meyer