Volume 10, Abstract Book BSTH, February 2019

Index

POSTER PRESENTATIONS: CLINICAL & LABORATORY

P24 IMPROVEMENT OF CHROMOGENIC ANTI-XA ASSAY TO MEASURE BETRIXABAN CONCENTRATION IN PLASMA

R. Siriez, J. Evrard, J-M. Dogné, L. Pochet, C. Bouvy, S. Lessire, F. Mullier, J. Douxfils


P25 CLOT WAVEFORM ANALYSIS: DETERMINATION OF OPTIMAL WAVELENGTH TO ASSESS THE FIBRIN COAGULATION PROCESS

J. Evrard, R. Siriez, L. Morimont, F. Mullier, J-M. Dogné, J. Douxfils


P26 ASSESSMENT OF INNER-FILTER OF THE REAGENTS OF THE COAGULATION PATHWAY ON BASELINE ABSORBANCE IN CLOT WAVEFORM ANALYSIS

J. Evrard, R. Siriez, L. Morimont, F. Mullier, J-M. Dogné, J. Douxfils


P27 VON WILLEBRAND FACTOR DEFICIENCY DOES NOT INFLUENCE ANGIOTENSIN I I-INDUCED ABDOMINAL AORTIC ANEURYSM FORMATION IN MICE

I. Portier, K. Martinod, L. Desender, N. VanDePutte, H. Deckmyn, K. VanHoorelbeke, S.F. De Meyer


P28 THE MECHANISM OF THE LOSS OF HMW VWF MULTIMERS AFTER LEFT VENTRICULAR ASSIST DEVICE IMPLANTATION IS DIFFERENT BETWEEN HUMANS AND SHEEP

S. Deconinck, A.-S. Schelpe, S. Jacobs, C. Nix, S. Barth, H.B. Feys, N. VanDePutte, C. Tersteeg, H. Deckmyn, S.F. De Meyer, B. Meyns, K. VanHoorelbeke


P29 WHY DO SOME GRAFTS, USED IN RVOT (RIGHT VENTRICULAR OUTFLOW TRACT) REVALVULATION, GET INFECTED AND OTHERS DO NOT?

B. Ditkowski, M. Bezulskaditkowska, R. Veloso, R. Jashari, M. Gewillig, M. Hoylaerts, B. Meyns, R. Heying


P30 VWF DEFICIENCY IS ASSOCIATED WITH RETICULOCYTOSIS AND INCREASED PARASITE ACCUMULATION IN EXPERIMENTAL MALARIA-ASSOCIATED ACUTE RESPIRATORY DISTRESS SYNDROME

S. Kraisin, S. Verhenne, T.-T. Pham, K. Martinod, I. Portier, N. VanDePutte, H. Deckmyn, K. VanHoorelbeke, P.E. Van Den Steen, S.F. De Meyer


P01 EVALUATION OF THE COBAS T 711 COAGULATION ANALYSER: A SINGLE CENTER EXPERIENCE

C. Orlando, S. Damiaens, Ö. Belce, K. Jochmans


P02 A CHALLENGING CASE OF ACQUIRED HAEMOPHILIA MANIFESTING AS HAEMATURIA

C. Lecut, M. Joiret, A. Gothot, P. Péters


P03 PREVALENCE OF HETEROZYGOUS TYPE 2N VON WILLEBRAND DISEASE MUTATIONS IN A BELGIAN SURVEY

I. Vangenechten, J. Jongenotter, K. Jochmans, C. Orlando, A. Gothot, K. Vandenbosch, A. Gadisseur


P04 DIFFERENCES IN FVIII MEASUREMENTS OF PLASMA SPIKED WITH AFSTYLA® GENERATED WITH ONE-STAGE CLOTTING ASSAY USING DIFFERENT COMMERCIAL APTT REAGENTS COMPARED WITH CHROMOGENIC METHOD

I. Vangenechten, M. Maes, A. Gadisseur


P05 DIFFERENCES IN ACTIVITY OF PLASMA SPIKED WITH IDELVION® GENERATED WITH ONE-STAGE CLOTTING ASSAY USING DIFFERENT COMMERCIAL APTT REAGENTS COMPARED WITH CHROMOGENIC METHOD

I. Vangenechten, M. Maes, A. Gadisseur


P06 EVALUATION OF VON WILLEBRAND FACTOR MULTIMER DISTRIBUTION USING A NEW SEMI-AUTOMATED VON WILLEBRAND MULTIMERIC ASSAY, HYDRAGEL VW MULTIMER (SEBIA)

I. Vangenechten, A. Gadisseur


P07 EVALUATION OF AN AUTOMATED VON WILLEBRAND FACTOR COLLAGEN BINDING ASSAY, HEMOSIL® ACUSTAR® VWF:CB

I. Vangenechten, M. Maes, A. Gadisseur


P08 RESOLVING DOAC INTERFERENCE ON APTT, PT AND LUPUS ANTICOAGULANT TESTING BY THE USE OF ACTIVATED CARBON

G. Frans, E.j.a. Bailleul, P. Meeus


P09 COMPARISON OF THE EFFECT OF MANUAL SAMPLE TRANSPORT AND TWO DIFFERENT PNEUMATIC TRANSPORTATION SYSTEMS ON COAGULATION ASSAYS

P. De Kesel, K. Devreese


P10 METHOD VALIDATION OF THE NEW STAGO PT REAGENT STANEOPTIMAL FOR PT/INR MEASUREMENT

L. Florin, P. De Kesel, K. Devreese


P11 EFFECT OF UNFRACTIONATED HEPARIN AND LOW MOLECULAR WEIGHT HEPARIN ON THE MEASUREMENT OF PT WITH TWO STAGO PT REAGENTS

L. Florin, P. De Kesel, K. Devreese


P12 SENSITIVITY OF THE NEW STAGO PT STA-NEOPTIMAL REAGENT FOR FACTOR DEFICIENCY ON STAGO STA-R EVOLUTION

L. Florin, P. De Kesel, K. Devreese


P13 THE VALUE OF LABORATORY SCREENING VS. CLINICAL JUDGMENT IN HIT DIAGNOSIS: EXPERIENCES IN THREE BELGIAN HOSPITALS

K. Eeckhout, G. Glynis, J. Emmerechts, K. Schatteman, M-B. Maes, E. Bailleul


P14 PRELIMINARY EVALUATION OF ADAMTS-13 ANTIBODY TESTING

N. Van Den Eede, J. Van Den Bossche, K. Deiteren, R. Malfait, M-B. Maes


P15 OPTIMISATION OF THE CALIBRATION CURVE FOR THE ACCURATE MEASUREMENT OF LOW FVIII LEVELS WITH ONE-STAGE ASSAYS

D.l.j. Van Den Bossche, J. Toelen, K. Peerlinck, M. Jacquemin


P16 HOW TO DEAL WITH SAMPLES WITH ERRORS ON APTT, PT AND FIBRINOGEN DUE TO OPTICAL CLOT DETECTION?

K. Eeckhout, J. Van Den Bossche, K. Deiteren, R. Malfait, M-B. Maes


P17 ESTABLISHMENT OF A THROMBIN GENERATION THRESHOLD IN SEVERE HAEMOPHILIAC PATIENTS UNDER PROPHYLAXIS TO FURTHER DETERMINE AN ADDED VALUE OF THIS TEST IN THE PERSONALIZED TREATMENT: A PILOT STUDY

L.r. Rozen, N. Moszynski, P.-Q. Le, P. Péters, A. Demulder


P18 EVALUATION OF THE TAV8® (STAGO) AGGREGOMETER IN THE CLINICAL LABORATORY

L. Schotte, K. Schatteman


P19 EVALUATION OF AN AUTOMATED LIGHT TRANSMISSION AGGREGOMETRY

D. Gobin, C. Collard, I. Droushout, A. Demulder, B. Cantinieaux


P20 EVALUATION OF THE NEW KIT STA-VWF RCO (STAGO) MEASURING WILLEBRAND FACTOR ACTIVITY AND COMPARISON WITH TWO SIEMENS KITS: BC VON WILLEBRAND REAGENT AND INNOVANCE VW ACTIVITY

C.w. Goudji, I. Courtois, J. Yernaux, M. Blauwaert, D. Govaerts, P. Cauchie


P21 A NOVEL ADAMTS13 CONFORMATION ELISA SHOWS CONFORMATIONAL ACTIVATION OF RAT ADAMTS13 WITH EXPOSURE OF CRYPTIC EPITOPES IN VITRO

C. Dekimpe, L.c. VelÁsquez Pereira, J. Voorberg, H. Deckmyn, S.F. De Meyer, K. VanHoorelbeke


P22 ANTI-CUB1 OR ANTI-SPACER ANTIBODIES THAT INCREASE ADAMTS13 ACTIVITY ACT BY ALLOSTERICALLY ENHANCING METALLOPROTEASE DOMAIN FUNCTION

A.-S. Schelpe, A. Petri, N. VanDePutte, H. Deckmyn, S.F. De Meyer, J.t.b. Crawley, K. VanHoorelbeke


P23 BETRIXABAN: IMPACT ON ROUTINE AND SPECIFIC COAGULATION ASSAYS - A PRACTICAL LABORATORY GUIDE

R. Siriez, J. Evrard, J-M. Dogné, L. Pochet, F. Mullier, J. Douxfils


Program

Program


EDUCATIONAL I

Should we measure DOACs?

J. Beekwilder, T. Feys


STATE OF THE ART I

State of the Art I: Thrombosis

T. Feys


PROFESSOR GASTON BAELE MEMORIAL LECTURE

Accomplishments and prospects in haemostasis

J. Beekwilder, T. Feys


EDUCATIONAL II

The new mechanism of autoimmunity is a HIT

J. Beekwilder, T. Feys


STATE OF THE ART II

Micro-organisms and coagulation

J. Beekwilder, T. Feys


ABSTRACTS EDUCATIONAL I

SHOULD WE MEASURE DOACS?

J. Douxfils


ORAL PRESENTATIONS: CLINICAL & LABORATORY

O01 INHERITED ANTITHROMBIN DEFICIENCY AND THROMBOSIS IN CHILDHOOD: DATA FROM A LARGE MULTICENTRIC COHORT

C. Orlando, B. De La Morena-barrio, M.e. De La Morena-barrio, V. Vicente, J. Corral, K. Jochmans


O02 PLATELET-RICH BUT NOT RBC-RICH AREAS IN STROKE THROMBI CONSIST OF DENSE FIBRIN STRUCTURES, VWF AND EXTRACELLULAR DNA

S. Staessens, F. Denorme, O. François, L. Desender, T. Dewaele, P. Vanacker, H. Deckmyn, K. VanHoorelbeke, T. Andersson, S.F. De Meyer


O03 LUPUS ANTICOAGULANT HYPOPROTHROMBINAEMIA SYNDROME: A PAEDIATRIC CASE REPORT

S. Vandamme, K. Ver Elst, M-B. Maes, S. Vermeiren


O04 THE PRESENCE OF ANTI-ADAMTS13 AUTO-ANTIBODIES DOES NOT CHANGE ADAMTS13 ANTIGEN LEVELS MEASURED BY AN IN HOUSE DEVELOPED ADAMTS13 ANTIGEN ELISA

C. Dekimpe, C. Tersteeg, E. Roose, C. Vendramin, N. VanDePutte, I. Pareyn, A. Vandenbulcke, H. Deckmyn, M. Scully, E. Tellier, S.F. De Meyer, K. VanHoorelbeke


O05 THE CONCENTRATION OF GP1BA MAGNETIC PARTICLES IS A CRITICAL PARAMETER OCCASIONALLY RESPONSIBLE FOR POOR REPRODUCIBILITY OF THE VWF:RCO WITH A CHEMILUMINESCENT IMMUNOASSAY

B. Calcoen, I. Van Horenbeeck, M. Debasse, J. Toelen, I. Vanlinthout, J. Schoeters, K. Peerlinck, M. Jacquemin


O06 OPEN ADAMTS13 CONFORMATION IN IMMUNE-MEDIATED THROMBOTIC THROMBOCYTOPENIC PURPURA IS INDUCED BY ANTI-ADAMTS13 AUTOANTIBODIES

E. Roose, A.-S. Schelpe, E. Tellier, G. Sinkovits, G. Kaplanski, M. Le Besnerais, I. Mancini, H.B. Feys, N. VanDePutte, A. Vandenbulcke, I. Pareyn, J. Voorberg, A. Greinacher, Y. Benhamou, H. Deckmyn, R. Fijnheer, Z. ProhÁszka, F. Peyvandi, P. Coppo, S.F. De Meyer, A. Veyradier, K. VanHoorelbeke


O07 THE VWF-GPIB INTERACTION MEDIATES THROMBO-INFLAMMATION IN EXPERIMENTAL STROKE VIA RECRUITMENT OF MONOCYTES, NEUTROPHILS AND T-CELLS TO THE BRAIN

F. Denorme, K. Martinod, A. Vandenbulcke, C.v. Denis, P.j. Lenting, H. Deckmyn, K. VanHoorelbeke, S.F. De Meyer


O08 THE DIFFERENTIAL ROLE OF PLATELETS AND FIBRIN IN ADHESION ON INFLAMED AND DAMAGED VALVES IN A NEW MOUSE MODEL OF EARLY STAPHYLOCOCCUS AUREUS ENDOCARDITIS


O09 VISUALIZING DENSE GRANULE FORMATION IN MEGAKARYOCYTES USING ADVANCED MICROSCOPY AND ITS APPLICATION FOR HERMANSKY-PUDLAK SYNDROME

J. Heremans, C. Thys, K. Cludts, V. Labarque, C. Van Geet, K. Freson


O10 P2X1 DEFICIENCY CAUSES MASSIVE INTESTINAL BLEEDING ALONG WITH ENHANCED NEUTROPHIL-DEPENDENT THROMBOSIS IN COLITIS

O. Wéra, L. Servais, C. Delierneux, A. Hego, C. Lecut, A. Keutgens, P. Delvenne, A. Nchimi, P. Lancellotti, C. Oury


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