Acute myeloid leukaemia (AML) is a disease of the elderly, with more than 75% of cases being diagnosed at 55 years or older. In these patients (>60 years), the disease prognosis is poor compared to younger patients. During the 2023 General Annual Meeting of the Belgian Hematology Society, Dr. Fabio Andreozzi (Jules Bordet Institute, Belgium) discussed the management of these elderly AML patients, with a focus on prognostic assessment, current treatment options and future perspectives.