During the last years several phase III studies comparing targeted agents (alone or in combination) to conventional chemo immunotherapy (CIT) have been published in chronic lymphocytic leukaemia (CLL) and small lymphocytic leukaemia (SLL). EHA 2019 featured several presentations on the most recent progress in this field. A selection of abstracts, as well as their impact on clinical practice, are discussed below.

(BELG J HEMATOL 2019;10(5):214–9)