AML is an extremely complex and heterogeneous disease. It is also a disease of the elderly, with a median age at diagnosis of 68 years and one third of the patients being older than 75 years. These factors make treatment of AML challenging and there is still a high unmet need to improve survival and QOL for the majority of AML patients.

(BELG J HEMATOL 2021;12(1):22-4)