Leading topics at the international symposium Acute Leukaemias (ISALXVIII) in 2023 were: the new classifications for acute leukaemia, interpretation of clonal haematopoiesis (CHIP), advancing insights of venetoclax-azacitidine (VEN-AZA) administration and associated supportive care, the position of new treatment options in fit and unfit patients, the renewed role of maintenance, and first steps in bringing immunotherapy to the acute myeloid leukaemia (AML) population.

(BELG J HEMATOL 2023;14(4):186–91)