Whole-exome sequencing studies have already uncovered some cancer drivers in chronic lymphocytic leukaemia (CLL) and have provided insights in disease pathogenesis, evolution and prognostication. At the 2015 annual EHA meeting in Vienna, Prof. Dr. Eugen Tausch (Universität Ulm) presented data of whole-exome sequencing of samples of 278 patients in the CLL8 trial.

(BELG J HEMATOL 2015;6(3):96–7)