Journal issues > Issue 4, July 2025 > Desensitisation as treatment option in patients with drug hypersensitivity

Desensitisation as treatment option in patients with drug hypersensitivity

By: E.M. Hutten MD, H. Dijkstra MD, M. Jalving MD, W.W.H. Roeloffzen MD, H.N.G. Oude Elberink MD, A.A.J.M. van de Ven MD

SUMMARY

Allergic reactions to drugs are a common problem. Desensitisation is a procedure in which temporary tolerance can be achieved to medication that previously induced hypersensitivity reactions. Successful desensitisation with chemotherapeutic agents and biologicals can ensure that patients can continue to receive the first-choice therapy. This review first examines the background of hypersensitivity reactions and desensitisation therapy. Subsequently, cases are described with different types of hypersensitivity reactions followed by subsequent successful desensitisation treatments.

(BELG J HEMATOL 2025;16(4):160–8)

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