Journal issues > Issue 2, March 2019 > Clinical and biologic correlates of frailty in older patients with malignant hemopathies

Clinical and biologic correlates of frailty in older patients with malignant hemopathies

By: S. Dubruille PhD, V. Thibaud MD, T. Pepersack MD, PhD, D. Bron MD, PhD

Frailty assessment in older patients with malignant hemopathies is very useful in order to improve care and treatment options. However, some lacks of data exist regarding the unsuspected frail population in presumed ‘clinically fit’ patients who should not benefit from chemotherapy. In this article, we review current data regarding prognostic factors and frailty scoring in older patients with malignant hemopathies. Prospective trials are needed to build a new frailty scoring to assess the unsuspected frail population in ‘clinically fit’ patients including specifically assessment of cognitive impairment.

(BELG J HEMATOL 2019;10(2):65–8)

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