In recent years, we have witnessed many advances in laboratory technology to detect germline or somatic mutations that predispose individuals to the development of haematopoietic malignancies. The laboratory technology session during the BHS GAM kicked off with a presentation from Dr. Ann Debecker explaining the differences between CHIP, CHOP and ARCH. In a second lecture of the laboratory technology session, Dr. Ine Moors provided a contemporary overview on genetic predisposition for myeloid malignancies.