Fatal Myceliophthora thermophila infection in a boy with acute myeloid leukaemia and cord blood stem cell transplantation

BJH - volume 5, issue 2, june 2014

A. Piette MD, B. De Moerloose MD, PhD, P. Schelstraete MD, PhD, V. Bordon MD, PhD, T. De Baere PhD, G. Claeys MD, PhD


We report a Myceliophthora thermophila infection in a boy who underwent haematopoietic (cord blood) stem cell transplantation as treatment for relapsed acute myeloid leukaemia. Despite neutrophil engraftment and maximal supportive treatment, the child died of multi-organ failure. Infections with environmental moulds are rare, but potentially disastrous in immunocompromised patients. Rapid diagnosis and early treatment is of upmost importance.

(BELG J HEMATOL 2014;5(2):60–3)

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