BJH - volume 12, issue 7, november 2021
G. Sqalli MD, T. Connerotte MD, B. Lambert MD, L. Dierge PharmD, T. Roy , J. Simar MD
We report the case of a 64-year-old patient, known for follicular lymphoma, admitted with facial paralysis accompanied by acute cervicobrachialgia. A lumbar puncture revealed the presence of centroblastic lymphoma cells whose clonal nature was confirmed by immunophenotyping. The histological examination of a lymph node biopsy was consistent with Burkitt-like high-grade lymphoma. Cytogenetic analysis showed the concomitant presence of a rearrangement of MYC as well as of BCL2 and BCL6. A final diagnosis of “triple-hit” high-grade B cell lymphoma (HGBL) was thus made. This entity belongs to the HGBL category of the WHO 2016 classification and shares characteristics with diffuse large B-cell lymphoma and Burkitt lymphoma. The diagnosis of this entity can be complex, in particular in view of a significant morphological variability. The cytogenetic work-up is thus essential for the differential diagnosis.
(BELG J HEMATOL 2021;12(7):318–22)
Read moreBJH - 2018, issue Abstract Book BHS, february 2018
S. Dupriez , A. Ferrant , M-C. Vekemans MD, B. Brichard MD, PhD, L. Michaux MD, PhD, T. Connerotte MD, E. Van den Neste MD, PhD, C. Vermylen , L. Knoops MD, PhD, C. Graux MD, PhD, F. Duhoux MD, PhD, C. Lambert MD, X. Poiré MD, PhD, H.A. Poirel MD, PhD
BJH - 2018, issue Abstract Book BHS, february 2018
A. Capes , F. Dall’Armellina , Y. Berners , L. Maindiaux , T. Connerotte MD, A. Camboni MD, PhD, P. Saussoy MD, PhD, J-P. Defour PhD, X. Poiré MD, PhD, N. Straetmans MD, PhD, M-C. Vekemans MD
BJH - volume 8, issue Abstract Book BHS, february 2017
G. Dachy , T. Connerotte MD
BJH - volume 7, issue Abstract Book BHS, january 2016
F. Van Obbergh MD, L. Knoops MD, PhD, Y. Beguin MD, PhD, C. Graux MD, PhD, S. Benghiat MD, PhD, K. Kargar-Samani , D. Bauwens , A. Efira MD, C. Dubois , C. Springael MD, PhD, L. Montfort , T. Connerotte MD, A. Delannoy , P. Wallemacq
BJH - 2013, issue BHS Abstractbook, january 2013
P. André , E. Van den Neste MD, PhD, G. Verhoef MD, PhD, D. Bron MD, PhD, A. Van Hoof MD, PhD, P. Zachée MD, PhD, S. van Steenwegen , B. De Prijck MD, N. Straetmans MD, PhD, M. Maerevoet MD, D. Boulet , F. Offner MD, PhD, P. Pierre , V. Mathieux MD, PhD, P. Mineur MD, T. Connerotte MD, M. Federico , J. Raemaekers
BJH - 2013, issue BHS Abstractbook, january 2013
S. Vidrequin , K. Rack PhD, M. Devos , T. Connerotte MD
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