Articles

Clinical case: High grade “triple hit” Lymphoma

BJH - volume 12, issue 7, november 2021

G. Sqalli MD, T. Connerotte MD, B. Lambert MD, L. Dierge PharmD, T. Roy , J. Simar MD

SUMMARY

We report the case of a 64-year-old patient, known for follicular lymphoma, admitted with facial paralysis accompanied by acute cervicobrachialgia. A lumbar puncture revealed the presence of centroblastic lymphoma cells whose clonal nature was confirmed by immunophenotyping. The histological examination of a lymph node biopsy was consistent with Burkitt-like high-grade lymphoma. Cytogenetic analysis showed the concomitant presence of a rearrangement of MYC as well as of BCL2 and BCL6. A final diagnosis of “triple-hit” high-grade B cell lymphoma (HGBL) was thus made. This entity belongs to the HGBL category of the WHO 2016 classification and shares characteristics with diffuse large B-cell lymphoma and Burkitt lymphoma. The diagnosis of this entity can be complex, in particular in view of a significant morphological variability. The cytogenetic work-up is thus essential for the differential diagnosis.

(BELG J HEMATOL 2021;12(7):318–22)

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PP06 Hereditary predisposition syndromes to malignant hemopathies (HPSMH)

BJH - 2018, issue Abstract Book BHS, february 2018

S. Dupriez , A. Ferrant , M-C. Vekemans MD, PhD, B. Brichard MD, PhD, L. Michaux MD, PhD, T. Connerotte MD, E. Van den Neste MD, PhD, C. Vermylen , L. Knoops MD, PhD, C. Graux MD, PhD, F. Duhoux , C. Lambert MD, X. Poiré MD, PhD, H.A. Poirel MD, PhD

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P61 Drug induced neutropenia with myelodysplasia with blast excess

BJH - 2018, issue Abstract Book BHS, february 2018

A. Capes , F. Dall’Armellina , Y. Berners , L. Maindiaux , T. Connerotte MD, A. Camboni MD, PhD, P. Saussoy MD, PhD, J-P. Defour PhD, X. Poiré MD, PhD, N. Straetmans MD, PhD, M-C. Vekemans MD, PhD

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P19 Vanishing bile duct syndrome associated with diffuse large B-cell lymphoma

BJH - volume 8, issue Abstract Book BHS, february 2017

G. Dachy , T. Connerotte MD

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PP4.2 The clinical relevance of imatinib (Im) plasma trough concentration in patients with chronic myelocytic leukemia (CML) in chronic phase. A Belgian retrospective study

BJH - volume 7, issue Abstract Book BHS, january 2016

F. Van Obbergh MD, L. Knoops MD, PhD, Y. Beguin MD, PhD, C. Graux MD, PhD, S. Benghiat MD, PhD, K. Kargar-Samani , D. Bauwens , A. Efira MD, C. Dubois , C. Springael MD, PhD, L. Montfort , T. Connerotte MD, A. Delannoy , P. Wallemacq

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P.07 Interim analysis of the randomized EORTC/ LYSA/FIL Intergroup H10 trial on early PET-scan driven treatment adaptation in stage I/II Hodgkin lymphoma

BJH - 2013, issue BHS Abstractbook, january 2013

P. André , E. Van den Neste MD, PhD, G. Verhoef MD, PhD, D. Bron MD, PhD, A. Van Hoof MD, PhD, P. Zachée MD, PhD, S. van Steenwegen , B. De Prijck MD, N. Straetmans MD, PhD, M. Maerevoet MD, D. Boulet , F. Offner MD, PhD, P. Pierre , V. Mathieux MD, PhD, P. Mineur MD, T. Connerotte MD, M. Federico , J. Raemaekers

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P.40 Hyperhaploid plasma cell myeloma: a rare case report

BJH - 2013, issue BHS Abstractbook, january 2013

S. Vidrequin , K. Rack PhD, M. Devos , T. Connerotte MD

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