Rhabdomyosarcoma mimicking acute leukaemia diagnosed on bone marrow

BJH - volume 11, issue 7, november 2020

J. Deuson MD, C. Motet MD, L. Delval MD, A-L. Trepant MD, J. Brauner MD


A 65-year-old woman presented with thrombocytopenia. A bone marrow biopsy was done and showed a cellular bone marrow infiltration by 94% of blast-like cells making the diagnosis of acute leukaemia. However, flow cytometry excluded hematological malignancy. After an extensive panel of immunohistochemical stains and genetic analysis, the diagnosis of metastatic alveolar rhabdomyosarcoma was made.

(BELG J HEMATOL 2020;11(7):317-9)

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