E. Philipse MD, T. Martens MD, A. Bufi MD, M. Kockx MD, P. Zachée MD, PhD, K. Wu MD, PhD
A 16-year-old Moroccan woman was referred to our centre because of bilateral cervical lymphadenopathy, high fever and weight loss. A malignant lymphoma was suspected in the lymph node biopsy. Histopathologic review of the lymph node biopsy showed extensive necrosis and nuclear debris with no viable remaining cells. A new lymph node biopsy was performed and the diagnosis of histiocytic necrotising lymphadenitis (Kikuchi-Fujimoto disease) was made. This is a rare, benign and self-limiting disease that mainly affects young women.