Articles

Recent advances in targeted therapies for patients with acute myeloid leukemia

BJH - 2023, issue Recent highlights in Acute Leukemia, october 2023

T. Feys MBA, MSc

Over the last decade, major advances in the molecular profiling of acute myeloid leukemia (AML) led to a deeper understanding of its pathobiology and revealed potential therapeutic vulnerabilities. As a result, the classification of AML subtypes has evolved from a morphologic to a molecular and genetic basis. After years of stagnation, we have recently witnessed a rapid expansion of the therapeutic armamentarium for AML. Apart from the use of low-intensity induction therapy with hypomethylating agents and venetoclax in patients who are ineligible for intensive chemotherapy, this includes the introduction of targeted agents for the treatment of AML patients harboring specific driver mutations.

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Moving from salvage chemotherapy to immunotherapy in patients with B-cell acute lymphoblastic leukemia

BJH - 2023, issue Recent highlights in Acute Leukemia, october 2023

T. Feys MBA, MSc

About half of the adult patients with acute B-cell lymphoblastic leukemia (B-ALL) who do not achieve a molecular complete remission or who subsequently relapse cannot be cured with the current chemotherapy or targeted agents. In recent years, however, we have witnessed the emergence of different immune-based therapies in this setting. This includes monoclonal antibodies, bispecific T-cell engagers (BiTEs), antibodydrug conjugates (ADCs), and chimeric antigen receptor T-cells (CARs).

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New haematology reimbursements in Belgium

BJH - volume 14, issue 5, september 2023

T. Feys MBA, MSc

OVERVIEW OF BELGIAN REIMBURSEMENT NEWS

(BELG J HEMATOL 2023;14(5):230–1)

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Journal scan

BJH - volume 14, issue 4, june 2023

J. Blokken PhD, PharmD, T. Feys MBA, MSc

SUMMARY

In this section of the Belgian Journal of Hematology (BJH), we aim to provide a snapshot of pivotal studies published in recent issues of the most important international journals focusing on haematology. Importantly, the selection of the studies discussed here is the sole responsibility of the publisher and was not influenced by third parties. Do you miss an important study, or did you read a hidden jewel that deserves to be shared with your colleagues? Please, let us know (editor@bjh.be) and we will make sure to include it in the journal scan section of the next BJH issue.

(BELG J HEMATOL 2023;14(4):192–5)

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New haematology reimbursements in Belgium

BJH - volume 14, issue 4, june 2023

T. Feys MBA, MSc

OVERVIEW OF BELGIAN REIMBURSEMENT NEWS

(BELG J HEMATOL 2023;14(4):196)

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Journal Scan

BJH - volume 14, issue 3, may 2023

J. Blokken PhD, PharmD, T. Feys MBA, MSc

SUMMARY

In this section of the Belgian Journal of Hematology (BJH), we aim to provide a snapshot of pivotal studies published in recent issues of the most important international journals focusing on haematology. Importantly, the selection of the studies discussed here is the sole responsibility of the publisher and was not influenced by third parties. Do you miss an important study, or did you read a hidden jewel that deserves to be shared with your colleagues? Please, let us know (editor@bjh.be) and we will make sure to include it in the journal scan section of the next BJH issue.

(BELG J HEMATOL 2023;14(3):145–8)

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New haematology reimbursements in Belgium

BJH - volume 14, issue 3, may 2023

T. Feys MBA, MSc

OVERVIEW OF BELGIAN REIMBURSEMENT NEWS

(BELG J HEMATOL 2023;14(3):149)

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